WebAug 31, 2024 · INTRODUCTION. Gout is an inflammatory arthritis due to monosodium urate crystal deposition disease. The long-term goals of therapy in patients who have already experienced signs and symptoms of the disease (established gout) are to prevent recurrent gout flares and to reverse prior signs of the disease by achieving and maintaining … WebObjectives The treat-to-target (T2T) concept has been applied successfully in several inflammatory rheumatic diseases. Gout is a chronic disease with a high burden of pain and inflammation. Because the pathogenesis of gout is strongly related to serum urate levels, gout may be an ideal disease in which to apply a T2T approach. Our aim was to develop …
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WebMar 17, 2024 · Pharmacologic goals include minimizing the inflammation and pain of an acute gout attack and preventing future gout flares. Initial urate-lowering therapy (ULT) usually consists of diet modification. Pharmacologic therapy lowers serum urate by either reducing the production or increasing the excretion of serum urate. 1. WebMar 5, 2024 · Gout Treatment Strategy . Once gout is definitively diagnosed, treatment is dependent on a global strategy that includes five clinical aims, each of which is discussed in detail elsewhere in this book: 1. Evaluation of hyperuricemia and its causes via disorders of renal urate disposition and/or of uric acid production (see Chapter 3 , Chapter 4 ... rooms for rent in selma nc
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WebMar 16, 2024 · Three aspects were considered in defining increasingly intensive strategies: (1) continuation of urate-lowering therapy, (2) serum urate monitoring, and (3) modification of urate-lowering therapy when serum urate >6mg/dL. We applied the “clone-censor-weight” method to account for baseline and time-varying confounding. WebDefine gout. gout synonyms, gout pronunciation, gout translation, English dictionary definition of gout. n. 1. A disturbance of uric-acid metabolism occurring chiefly in males, … WebMar 30, 2024 · Gout presents as intermittent episodes of severely painful arthritis (gout flares) caused by the innate immune response to deposited monosodium urate crystals. … rooms for rent in secaucus nj