2024 Htatsf1 topbp1

Htatsf1 topbp1

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August undefined, 2024

WebA PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination. The efficiency of homologous recombination … WebPMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35597237-5 2024 The localization of HTATSF1-TOPBP1 to DSBs is …

A PARylation-phosphorylation cascade promotes TOPBP1 loading …

Web21 jul. 2024 · HTATSF1 is an RNA-binding protein, and its RRMs are essential for the recruitment of TOPBP1. By inhibiting transcription and not observing a phenotype, the … Web1 jul. 2015 · (E) Topbp1 MO can block the translation of topbp1 mRNA. The topbp1 MO, as validated in S3 Fig, was injected into one-cell stage wild-type embryos to produce … pain and gain sa prevodom

TOPBP1 regulates RAD51 phosphorylation and chromatin loading …

Web15 feb. 2024 · In specific, HTATSF1 is phosphorylated by CK2 kinase at Ser748 and the phosphorylation mark is read by the N-terminal BRCA1 C-terminal (BRCT) domains of … Web20 mei 2024 · The localization of HTATSF1-TOPBP1 to DSBs is potentially independent of the transcription-coupled RNA-binding and processing capacity of HTATSF1 but rather … Web3 okt. 2024 · Human TopBP1 plays essential roles in DNA replication initiation, checkpoint signaling, and DNA repair and influences transcriptional control ( 3, 4 ). TopBP1 contains eight BRCA1 carboxyl-terminal (BRCT) phosphopeptide recognition motifs and an ATR-activating domain (AAD) ( 3, 4 ). stylist search

A PARylation-phosphorylation cascade promotes TOPBP1 loading …

CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer ...

Web25 jan. 2016 · TOPBP1 contains nine BRCT domains (Rappas et al., 2011) and an ATR-activation domain (Kumagai et al., 2006). First, we generated three large RNAi-resistant … WebFigure 1 . Molecular Cell 2024 822538-2540DOI: (10.1016/j.molcel.2024.06.038) Copyright © 2024 Elsevier Inc. Terms and Conditions. TOPBP1 recruitment to double ... pain and gain online freeWebTOPBP1 Antibodies. Antibodies that detect TOPBP1 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, … pain and gain points

"Web22 mei 2024 · Here, we report that TOPBP1 interacts with the RNA-binding protein HTATSF1 in a cell-cycle- and phosphorylation-dependent manner. Mechanistically, CK2 … " - Htatsf1 topbp1

Htatsf1 topbp1

WebA PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination Author links open overlay panel Jiao Zhao 1 4 , … WebA PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination. Authors - Jiao Zhao. KD Validated; View Article. …

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Web15 feb. 2024 · In specific, HTATSF1 is phosphorylated by CK2 kinase at Ser748 and the phosphorylation mark is read by the N-terminal BRCA1 C-terminal (BRCT) domains of … WebDNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line Elias ElInatia, Helen R. Russellb, Obah A. Ojarikrea, Mahesh Sangrithic, Takayuki Hirotaa, Dirk G. de Rooijd,e, Peter J. McKinnonb, and James M. A. Turnera,1 aSex Chromosome Biology Laboratory, The Francis Crick Institute, London …

WebBrowse HTATSF1 products, learn HTATSF1 Information And Facts common name: HIV TAT specific factor 1. Functions as a general transcription factor playing a role in the … Web"An in vitro transcription system that recapitulates equine infectious anemia virus tat-mediated inhibition of human immunodeficiency virus type 1 Tat activity demonstrates a role for positive transcription elongation factor b and associated proteins in the mechanism of Tat activation". Virology. 274 (2): 356–66. doi: 10.1006/viro.2000.0480.

Web14 okt. 2024 · HTATSF1-Nucleated PARylation and Phosphorylation Cascade Dictates Homologous Recombination and Modulates Chemotherapeutic Response of Breast … Web2 aug. 2024 · We report that TOPBP1 is only transiently present at DSBs, with a half-life of less than 10 minutes. We also examined the relationship between TOPBP1 and the …

WebHere, we report that TOPBP1 interacts with the RNA-binding protein HTATSF1 in a cell-cycle- and phosphorylation-dependent manner. Mechanistically, CK2 phosphorylates …

WebHere, we report that TOPBP1 interacts with the RNA-binding protein HTATSF1 in a cell-cycle- and phosphorylation-dependent manner. Mechanistically, CK2 phosphorylates … stylists goop crossword clueWebFor Flag-TopBP1 transfection, cells were plated 24 h before transfection in 100 mm dishes at 1 × 10 6 cells. 12.5 μg of pcDNA3-TopBP1 was mixed with 25 μl of Polyethylenimine … pain and gain online with subtitles in germanWebHTATSF1是S期TOPBP1结合蛋白 1、为了进一步了解HTATSF1-TOPBP1相互作用的分子机理，我们通过Co-IP，SPR实验等发现HTATSF1通过pS748负责与TOPBP1结合（图2） … pain and gain posterWeb10 mrt. 2024 · Here, we report that TOPBP1 interacts with the RNA-binding protein HTATSF1 in a cell-cycle- and phosphorylation-dependent manner. Mechanistically, CK2 … pain and gain ratedWeb5 mei 2024 · 7 State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Key Laboratory of Medical Data Analysis and Statistical Research of Tianjin, Nankai … pain and gain ratingWebHuman TopBP1 contains nine BRCT domains and functions in DNA replication initiation, checkpoint signalling, DNA repair and influences transcriptional control. TopBP1 and its … stylist short storiesWeb5 okt. 2024 · Together, our study reveals an S-phase specific HTATSF1-nucleated PARylation and phosphorylation cascade that directs the HR-promoting activity of … pain and gain real characters